Maine Cannabis Exchange’s recreational storefront at 27 Ocean Street, Suite 1 sits just over the Casco Bay Bridge in South Portland — an independently owned and operated dispensary founded in 2014 with a mission that began well before Maine’s recreational market existed. MCE was originally established to supply accurately dosed, easily administrable tinctures to children with neurological conditions through an affiliation with a local hospital’s neurology department, a founding story that still shapes the operation’s patient-first, education-based approach. The recreational store at 27 Ocean Street carries in-house cannabis flower and house-made extracts alongside products from local Maine vendors, with a clean, organized floor and knowledgeable staff — budtenders Joanna and Jericah are mentioned by name in reviews for their guidance and genuine care. Competitive pricing and a loyalty platform (text MAINE420 to 207-280-8399) make the store accessible to a range of customers. MCE also operates a dedicated medical store at 225 Waterman Drive in South Portland for registered medical patients. Note: the recreational storefront operates a split-shift schedule with a mid-day break — confirm current hours before visiting. Maine Cannabis Exchange suits recreational adults 21-plus in South Portland, Portland, and across the Casco Bay Bridge corridor who want a locally rooted, independently operated dispensary with in-house extracts, accessible pricing, and a staff culture built around genuine patient care since 2014.

Phone: (207) 221-2277 Address: 27 Ocean St, Suite 1, South Portland, ME 04106 Hours: Mon–Sun 10:00 AM–1:30 PM | 2:30 PM–6:00 PM (split shift; call to confirm current hours) Payment: Cash; debit; ATM on-site Nearby neighborhoods served: South Portland ME, Portland ME, Casco Bay Bridge corridor, Cumberland County ME Last verified: May 2026 Notes: 27 Ocean St Suite 1, South Portland; just over the Casco Bay Bridge; recreational storefront only (medical store at separate address: 225 Waterman Dr, South Portland); founded 2014; locally owned; in-house flower + house-made extracts + tinctures; local Maine vendors; loyalty program (text MAINE420 to 207-280-8399); ATM on-site; split-shift hours — call to confirm; official website (mainecannabisexchange.com) currently returning 404 — verify before publishing; Google rating not confirmed; Yelp March 2026 (34 photos); Weedmaps active; recreational (21+) Website: mainecannabisexchange.com