Trulieve is a Florida-licensed Medical Marijuana Treatment Center (MMTC) in Jacksonville, Florida. It sits at 10095 Beach Boulevard, Suite 450, in the Southside Estates area, zip code 32246. The dispensary operates under Florida license #MMTC-2015-0005. It is run by Trulieve Cannabis Corp. (CSE: TRUL / OTCQX: TCNNF). Trulieve serves registered patients across Jacksonville, the Southside, and Arlington.

Trulieve carries its full in-house brand portfolio. That includes Alchemy, Co2lors, Cultivar Collection, Modern Flower, Momenta, Muse, Roll One, Sweet Talk, and Trekkers. It also stocks partner brands such as Alien Labs, Connected, Khalifa Kush, Seed Junky, and Sunshine Cannabis. The menu spans flower, vapes, edibles, concentrates, tinctures, topicals, and RSO.

The store offers a walk-in retail floor with online ordering for express pickup, plus home delivery. Cash and CanPay are accepted, with an on-site ATM. First-time patients receive 60% off their first order, 50% off the second, and 40% off the third. Veterans receive 20% off, and seniors 55 and older receive 10% off. Hours are 9:00 AM to 8:45 PM Monday through Saturday, and 9:00 AM to 8:00 PM on Sunday. This Southside Estates store is one of several Trulieve dispensaries in Jacksonville. It is distinct from the separate Trulieve at 6259 Beach Boulevard and the San Jose Boulevard store.

What kind of dispensary is Trulieve Jacksonville Southside, and who is it for?

Trulieve Jacksonville Southside is a full-service medical cannabis dispensary. It serves registered Florida medical marijuana patients across Jacksonville and Duval County.

Does Trulieve Jacksonville Southside require a Florida medical marijuana card?

Yes. Trulieve operates as a Florida MMTC under OMMU licensing, and a valid Florida Medical Marijuana Card is required for all purchases.

Does Trulieve Jacksonville Southside accept out-of-state medical marijuana cards?

No. Florida’s MMTC program does not provide reciprocity for out-of-state medical cards.

Trulieve (formerly Harvest HOC) Phone: (904) 822-5633 Address: 10095 Beach Blvd, Suite 450, Jacksonville, FL 32246 Hours: Mon–Sat 9:00 AM–8:45 PM | Sun 9:00 AM–8:00 PM Payment: Cash, CanPay, ATM on-site Nearby neighborhoods served: Jacksonville FL, Southside FL, Arlington FL, Jacksonville Beach FL, Duval County FL Last verified: May 2026 Notes: Florida MMTC license #MMTC-2015-0005; Trulieve Cannabis Corp. (CSE: TRUL / OTCQX: TCNNF); 10095 Beach Blvd Suite 450 — Southside Estates, Jacksonville; hours/address/phone confirmed from official Trulieve site; full in-house portfolio Alchemy + Co2lors + Cultivar Collection + Modern Flower + Momenta + Muse + Roll One + Sweet Talk + Trekkers; partner brands Alien Labs + Connected + Khalifa Kush + Seed Junky + Sunshine Cannabis; flower + vapes + edibles + concentrates + tinctures + topicals + RSO; walk-in + express pickup + delivery; Cash + CanPay + ATM; new patient 60/50/40% first three orders; veteran 20%; senior 55+ 10%; one of several Trulieve Jacksonville stores — distinct from Trulieve 6259 Beach Blvd (32216) + Trulieve San Jose Blvd (10339) + Trulieve Jacksonville Beach + Trulieve Orange Park (342 Blanding Blvd); legacy site harvesthoc.com redirects to trulieve.com; open 7 days. Website: trulieve.com