AYR Cannabis Dispensary at 16810 US Highway 441, Unit 501, in Summerfield, Florida, operates as a Florida-licensed Medical Marijuana Treatment Center (MMTC) on US Highway 441 in the 34491 zip code in unincorporated Marion County — on the primary north-south arterial connecting Ocala to The Villages and the broader central Florida retirement corridor. Summerfield sits at the geographic heart of one of the most densely senior-populated regions of the United States, immediately south of Ocala and adjacent to The Villages, the master-planned retirement community with over 130,000 residents that represents the largest single patient demographic concentration in Florida’s MMTC market. Formerly operating as Liberty Health Sciences, the US 441 Summerfield location transitioned to the AYR Cannabis brand following AYR Wellness’s acquisition of Liberty Health Sciences’ Florida MMTC network. AYR carries a full product lineup at this location — flower, edibles, vape cartridges, pre-rolls, concentrates, and tinctures — including products from the kynd, Haze, Entourage, Secret Orchard, Nordic Wellness, and Levia brand portfolios, available for in-store shopping or online ordering with pickup. Free statewide delivery is available on orders over $50 with a $25 fee below that threshold. Patient discount programs include 50% off the first three purchases for new patients, 25% off for qualifying veterans, 15% off for senior patients 55 and older, and $75 off a $150 purchase for medical cardholders who renewed within the preceding 31 days. The dispensary operates seven days a week, Monday through Saturday at 9:00 AM through 8:30 PM and Sunday 10:00 AM through 8:00 PM.

Does AYR Cannabis Dispensary Summerfield require a Florida medical marijuana card? Yes — AYR operates as a Florida MMTC under OMMU licensing, and a valid Florida Medical Marijuana Card is required for all purchases.

Does AYR Cannabis Summerfield accept out-of-state medical marijuana cards? No — Florida’s MMTC program does not provide reciprocity for out-of-state medical cards.

AYR Cannabis Dispensary Phone: (352) 307-2177 Address: 16810 US Hwy 441, Unit 501, Summerfield, FL 34491 Hours: Mon–Sat 9:00 AM–8:30 PM | Sun 10:00 AM–8:00 PM Payment: Call to confirm Nearby neighborhoods served: Summerfield FL, Marion County FL, The Villages FL, Ocala FL, Belleview FL, Lady Lake FL, Leesburg FL Last verified: April 2026 Notes: Formerly Liberty Health Sciences; AYR Wellness / AYR Cannabis brand; Florida MMTC — Florida Medical Marijuana Card required; 16810 US Hwy 441 Unit 501 Summerfield Marion County; US 441 retirement corridor near The Villages; kynd + Haze + Entourage + Secret Orchard + Nordic Wellness + Levia brand products; flower + edibles + vapes + pre-rolls + concentrates + tinctures; online ordering + pickup; delivery free on $50+; new patient 50% off first 3 purchases; veteran 25% off; senior 55+ 15% off; medical card renewal $75 off $150; open 7 days. Website: ayrdispensaries.com