On Duval Street in Old Town Key West, Trulieve runs a medical cannabis dispensary. The store sits at 400 Duval Street, Unit C, Key West, Florida 33040. Trulieve holds Florida MMTC license #MMTC-2015-0005. It serves patients across Monroe County and the Lower Keys.

Trulieve grows its own cannabis and runs more than 180 dispensaries nationwide. Sweet Talk edibles, Cultivar flower, and partner brand Blue River anchor the menu. Flower, pre-rolls, vapes, concentrates, tinctures, topicals, capsules, and RSO fill the cases. Payment is cash or CanPay, with an ATM onsite.

First-time patients save 60%, veterans 20%, and seniors 55 and older 10%. Same-day pickup and Keys delivery are both available. Hours run 9:00 AM to 8:45 PM Monday through Saturday and 11:00 AM to 8:00 PM Sunday.

Duval Street runs through the heart of Old Town, lined with bars, shops, and galleries. Mallory Square, Sloppy Joe’s Bar, and the Southernmost Point sit within walking distance. Patients and visiting Florida cardholders come from across Key West and Stock Island.

Who is Trulieve Key West for?

Trulieve Key West serves registered Florida medical marijuana patients across Monroe County, from Old Town through Stock Island and the Lower Keys.

Can tourists buy here without a Florida card?

No. Florida accepts only its own medical cards, so an active Florida Medical Marijuana Card is required — out-of-state cards aren’t valid.

Is the dispensary on Duval Street?

Yes. It’s at 400 Duval Street, Unit C, in Old Town, within walking distance of Mallory Square and the Southernmost Point.

Trulieve Phone: (786) 652-9187 Address: 400 Duval St, Unit C, Key West, FL 33040 Hours: Mon–Sat 9:00 AM–8:45 PM; Sun 11:00 AM–8:00 PM Payment: Cash, CanPay, ATM onsite Nearby neighborhoods served: Key West FL, Old Town FL, Stock Island FL, Lower Keys FL, Monroe County FL Last verified: May 2026 Notes: Florida MMTC license #MMTC-2015-0005; operated by Trulieve; on Duval Street in Old Town Key West, within walking distance of Mallory Square, Sloppy Joe’s Bar, and the Southernmost Point; house brands Sweet Talk, Cultivar, Momenta, Roll One, and Co2lors plus partner brands Blue River and Khalifa Kush; flower + pre-rolls + vapes + edibles + concentrates + tinctures + topicals + capsules + RSO; cash + CanPay + ATM onsite; new patient 60%, veteran 20%, senior 55+ 10%; same-day pickup plus Florida Keys delivery; open 7 days. Website: trulieve.com/dispensaries/florida/key-west