Trulieve at 342 Blanding Boulevard in Orange Park, Florida, operates as a Florida-licensed Medical Marijuana Treatment Center (MMTC) on Clay County’s most commercially active corridor in the 32073 zip code — one of several licensed MMTCs clustered along the Blanding Boulevard strip that has made Orange Park one of the most MMTC-dense suburban markets in Northeast Florida relative to its population size. The 342 Blanding Boulevard location anchors the southern end of this cluster, serving qualified patients from Orange Park, Middleburg, Fleming Island, Green Cove Springs, and the rural Clay County communities that look to Blanding Boulevard as their primary commercial and healthcare access corridor. Trulieve carries its full in-house brand lineup and Florida-exclusive partner brands across flower, vapes, edibles, tinctures, topicals, concentrates, and RSO, with online ordering for pickup and home delivery throughout the Clay County service area. Delivery carries a $50 minimum with a $15 fee on orders below $100, and free delivery for qualifying patients 65 and older — a meaningful accessibility benefit for Orange Park’s substantial retiree and senior residential population. The dispensary holds a 4.2★ Google rating from 946 reviewers, reflecting years of patient activity in the Orange Park market. Payment accepted via cash, Canpay, and an on-site ATM. The Orange Park location opens at 9:00 AM seven days a week, with Monday through Saturday service through 8:45 PM and Sunday through 8:00 PM.

Does Trulieve Orange Park require a Florida medical marijuana card? Yes — Trulieve operates as a Florida MMTC under OMMU licensing, and a valid Florida Medical Marijuana Card is required for all purchases.

Does Trulieve Orange Park accept out-of-state medical marijuana cards? No — Florida’s MMTC program does not provide reciprocity for out-of-state medical cards.

Trulieve Phone: (904) 204-0140 Address: 342 Blanding Blvd, Orange Park, FL 32073 Hours: Mon–Sat 9:00 AM–8:45 PM | Sun 9:00 AM–8:00 PM Payment: Cash, Canpay, ATM on-site Nearby neighborhoods served: Orange Park FL, Clay County FL, Middleburg FL, Fleming Island FL, Green Cove Springs FL, Keystone Heights FL, Southwest Jacksonville FL Last verified: May 2026 Notes: Florida MMTC; 342 Blanding Blvd Orange Park Clay County; 4.2★ from 946 Google reviews; Trulieve in-house brands + Florida-exclusive partner brands; flower + vapes + edibles + tinctures + topicals + concentrates + RSO; Cash + Canpay + ATM; online ordering + pickup + delivery; $50 delivery minimum; $15 fee below $100; free delivery for patients 65+ with minimum order; open 7 days. Website: trulieve.com